研究方向：

1、聚焦骨相关疾病的发病机制及组织微环境，构建多种功能骨类器官；

2、通过生物微球系统构建多功能皮肤类器官

3、通过类器官模型解析生理及病理性生命现象，助力解决临床问题

代表性学术成果：

[1] Mengru Zhu^#, Hao Zhang^#, Qirong Zhou^#, Shihao Sheng^#, Qianmin Gao, Zhen Geng, Xiao Chen, Yuxiao Lai, Yingying Jing, Ke Xu, Long Bai, Guangchao Wang*, Jianhua Wang*, Yingying Jiang*, Jiacan Su*. Dynamic GelMA/DNA dual-network hydrogels promote woven bone organoid formation and enhance bone regeneration. Advanced Materials, 2025, 37, 2501254.(封面论文，ESI高被引)

[2] Xiang Wu^#, Fuxiao Wang^#, Ruiyang Li^#, Biao Yu^#, Tianhang Qi, Yunpeng Li, Xiao Chen, Jian Wang, Zhen Geng, Peiran Song, Long Bai, Dongyang Zhou*, Hou-Feng Zheng*, Qin Zhang*, Jiacan Su*. Enzyme-programmable DNA-PEG hydrogel spatiotemporally regulates bone regeneration microenvironment. Advanced Materials, 2025, 38(6): e14461.

[3] Tianhang Qi^#, Yunpeng Li^#, Yanan Guo^#, Shihao Sheng^#, Shujuan Jia, Shuling Zhou, Long Bai, Xiuhui Wang, Chongru He*, Zhen Geng*, Qin Zhang*, Jiacan Su*. Photothermal hydrogel with gel-sol transition for programmed antibacterial and wound healing. Advanced Functional Materials, 2026, DOI:10.1002/adfm.74776.

[4] Qin Zhang^#, Weikai Chen^#, Guangfeng Li^#, Zhixin Ma, Mengru Zhu, Qianmin Gao, Ke Xu, Xinru Liu, Wenyi Lu, Wencai Zhang*, Yan Wu*, Zhongmin Shi*, Jiacan Su*. A factor-free hydrogel with ROS scavenging and responsive degradation for enhanced diabetic bone healing. Small, 2024, 20(24): 2306389.

[5] Qianmin Gao^#, Yingying Jiang^#, *, Dongyang Zhou^#, Guangfeng Li^#, Yafei Han, Jingzhi Yang, Ke Xu, Yingying Jing, Long Bai, Zhen Geng, Hao Zhang, Guangyin Zhou, Mengru Zhu, Ning Ji, Ruina Han, Yuanwei Zhang, Zuhao Li, Chuandong Wang, Yan Hu, Hao Shen, Guangchao Wang, Zhongmin Shi, Qinglin Han*, Xiao Chen*, Jiacan Su*. Advanced glycation end products mediate biomineralization disorder in diabetic bone disease. Cell Reports Medicine, 2024, 5(9): 101694. (封面论文，ESI高被引)

[6] Weikai Chen^#, Shihao Sheng^#, Kai Tan^#, Sicheng Wang^#, Xiang Wu, Jiayi Yang, Yan Hu, Liehu Cao, Ke Xu, Fengjin Zhou*, Jiacan Su*, Qin Zhang*, Lei Yang*. Injectable hydrogels for bone regeneration with tunable degradability via peptide chirality modification. Materials Horizons, 2024, 11, 4367-4377.

[7] Mengru Zhu^#, Zhehao Fan^#, Mengshuo Chen^#, Ke Xu*, Yingying Jiang*, Jiacan Su*, Biomineralization empowers bone organoids. Biomaterials, 2026, 326, 123703.

[8] Xiang Wu^#, Yan Hu^#, Shihao Sheng^#, Huijian Yang^#, Zuhao Li*, Qinglin Han*, Qin Zhang*, Jiacan Su*. DNA-based hydrogels for bone regeneration: A promising tool for bone organoids. Materials Today Bio, 2025, 31, 101502. (ESI高被引)

[9] Yutong Chen^#, Mengru Zhu^#, Shihao Sheng^#, Huijian Yang^#, Qin Zhang, Xiao Chen, Ke Xu, Mengmeng Li, Biaotong Huang*, Qinglin Han*, Yingying Jiang*, Jiacan Su*. Biomimetic extracellular vesicles containing biominerals for targeted osteoporosis therapy. ACS Applied Materials & Interfaces, 2025, 17(4): 5823-5840.

[10] Yingying Jiang^#, Jiadong Li^#, Xu Xue^#, Zhifeng Yin*, Ke Xu*, Jiacan Su*, Engineered extracellular vesicles for bone therapy. Nano Today, 2022, 44: 101487. (ESI高被引)