研究方向：
致力于开发能够应用于衰老组织修复再生过程的活性多肽分子与仿生多肽材料
代表性学术成果：
1. Yejiao Shi, Gan Luo, Borui Zhen, Zhinan Liu, Sumeng Chen, Zhe Wang, Wuyuan Lu*, Honggang Hu*, Xiang Li*. Systematic all-hydrocarbon stapling analysis for cecropin a generates a potent and stable antimicrobial peptide. Journal of Medicinal Chemistry, 2025, 68, 6, 6372-6385.
2. Yejiao Shi, Huixuan Chen, Sumeng Chen, Xiangxiang Kong, Zhinan Liu, Shaojie Wu, Xiang Li, Kai Zheng*, Yan Xu*, Honggang Hu*. N-Terminal Lipidation of Buforin II Generates a Potent and Stable Peptide Antibiotic. Journal of Medicinal Chemistry, 2025, 68, 16, 17624-17637.
3. Xiangxiang Kong, Han Liu, Sumeng Chen, Zhinan Liu, Qin Chen, Xiang Li, Honggang Hu*, Jiacan Su*, Yejiao Shi*. Bioengineered bacterial extracellular vesicles for targeted delivery of an osteoclastogenesis-inhibitory peptide to alleviate osteoporosis. Journal of Controlled Release, 2025, 10, 382, 113751.
4. Zelin Zheng, Xi Liu, Kailu Guo, Shaojie Wu, Wenchen Cai, Yuting Li, Yirong Wang, Cuiping Zhang*, Honggang Hu*, Yejiao Shi*. Bioengineered probiotics derived bacterial extracellular vesicle as bioactive nanocarrier for the local VEGF expression to accelerate wound healing. Journal of Nanobiotechnology, 2026.
5. Hongrui Zhao, Yan Sheng*, Tenghua Zhang, Shujun Zhou, Yuqing Zhu, Feiyang Qian, Meiru Liu, Weixue Xu, Dengsong Zhang*, Jiaming Hu*. The CRISPR-Cas13a Gemini System for noncontiguous target RNA activation. Nature Communications, 2024, 15, 1, 2901.
6. Yan Sheng, Zena Huang, Tenghua Zhang, Feiyang Qian, Yuqing Zhu, Zaizai Dong, Qingyang Zhang, Qi Lei, Fanhui Kong, Yuqiong Wang, Maddie Walden, Stefan Wuttke, Lingqian Chang*, Wei Zhu*, Jiaming Hu*. Living Cell Nanoporation and Exosomal RNA Analysis platform for real-Time assessment of cellular therapies. Journal of the American Chemical Society, 2022, 144, 9443-9450.
7. Feiyang Qian, Zena Huang, Hankang Zhong, Qi Lei, Yiru Ai, Zihui Xie, Tenghua Zhang, Bowen Jiang, Wei Zhu*, Yan Sheng*, Jiaming Hu*, C. Jeffrey Brinker. Analysis and biomedical applications of functional cargo in extracellular vesicles. ACS Nano, 2022, 16, 19980-20001.
8. Yuting Li, Zelin Zheng, Xiangxiang Kong, Yirong Wang, Zhinan Liu, Wen Wang, Honggang Hu*, Feng Xu*, Yejiao Shi*. Bacteria extracellular vesicles derived from Lactobacillus reuteri delivering intrinsic miR-21a-5p to accelerate diabetic wound healing. Nano Research, 2025, 18, 94908083.
9. Yejiao Shi*, Yuting Li, Zhinan Liu, Xiangxiang Kong, Xiaochun Hu, Xi Liu*, Cuiping Zhang*, Honggang Hu*. Engineering bacterial extracellular vesicles as nanoweapons to fight against bacterial infections. Research, 9, 1135.
10. Yejiao Shi, Zelin Zheng, Yuting Li, Yirong Wang, Helena S. Azevedo, Xi Liu*, Cuiping Zhang*, Honggang Hu*. Bacterial extracellular vesicles as bioactive nanocarriers for wound treatment. Acta Pharmaceutica Sinica B, 2026.
