研究方向：
1. 基于类器官模型的微纳生物材料研究
2. 多功能骨类器官构建
代表性学术成果：
1. X. Chen#, D. Zhou#, J. Wang#, H. Liu#, H. Zhang, Z. Geng, G. Wang, H. Shen, Y. Zhang, Z. Li, D. Wang, X. Ren, X. Wang, K. Xu, C. He, L. Bai*, Y. Wei*, X. Chen*, J. Su*. Viral glycoprotein-mimicking peptide-functionalized micelles promote drug delivery to diseased chondrocytes for osteoarthritis alleviation. Nature Nanotechnology, 2025, 1-11.
2. J. Wang#, Y. Wu#, G. Li#, F. Zhou#, X. Wu, M. Wang, X. Liu, H. Tang, L. Bai, Z. Geng, P. Song*, Z. Shi*, X. Ren*, J. Su*, Engineering Large-Scale Self-Mineralizing Bone Organoids with Bone Matrix-Inspired Hydroxyapatite Hybrid Bioinks. Advanced Materials, 2024, 2309875.
3. Duan, N#, Li, J#, Song, S, Wang, F, Yang, Y, Nie, D, Wang, C, Sheng, Y, Tao, Y, Gao, J, Xu, C*, Wei, Y*, Gan, Y. Enzyme‐activated prodrug‐based smart liposomes specifically enhance tumor hemoperfusion with efficient drug delivery to pancreatic cancer cells and stellate cells. Advanced Functional Materials, 2021, 31(46): 2100605.
4. Y. Zhang#, F. Wang #, R. Li #, D. Huang #, Q. Gao, Q. Zhang, Z. Geng, L. Bai, J. Wang, Y. Jing, Y. Lai, Z. Cao*, H. Dou*, X. Ren *, J. Su *, Immune-Instructive Bone Organoids via Non-Immunogenic Plant-Based Bioinks for Enhanced Bone Repair. Matter, 2026, in press.
5. Y.Wei#, S.Song#, N. Duan, F. Wang, Y. Wang, Y. Yang, C.Peng, J.Li, D.Nie; X.Zhang,; , S.Guo; , C.Zhu; , M. Yu; , Y Gan *. MT1‐MMP‐Activated Liposomes to Improve Tumor Blood Perfusion and Drug Delivery for Enhanced Pancreatic Cancer Therapy. Adv. Sci., 2020, 1902746.
6. Y. Cheng, M. Xu, J. Wu, K. Qian, P. Yang, L. Zhou, R. Meng, Y. Li, T. Wang, D. Sheng, Y. Wei*, Q. Zhang*. Carcinoma–Astrocyte Gap Junction Interruption by a Dual-Targeted Biomimetic Liposomal System to Attenuate Chemoresistance and Treat Brain Metastasis. ACS nano, 2024, 18(50): 34107-34125.
7. J. Wu#, Y. Cheng#, K. Qian, P. Yang, L. Zhou, M. Xu, D. Sheng, T. Wang, Y. Li, X. Yang, Y. Wei*, Q. Zhang*. siRNA-encapsulated biomimetic liposomes effectively inhibit tumor cells’ Hexosamine biosynthesis pathway for attenuating hyaluronan barriers to pancreatic cancer chemotherapy. ACS nano, 2025, 19(8): 7928-7947.
8. J. Cao#, J. Wu#, P. Yang, K. Qian, Y. Cheng, M. Xu, D. Sheng, R. Meng, T. Wang, Y. Li, Y. Wei*, Q. Zhang *. Dual Enzyme Cascade-Activated Popcorn-Like Nanoparticles Efficiently Remodeled Stellate Cells to Alleviate Pancreatic Desmoplasia. ACS Nano, 2023, 17(20), 19793-19809.
9.D. Zhou#, Y. Wei#, S. Sheng#, M. Wang#, J. Lv, B. Zhao, X. Chen, K. Xu, L. Bai, Y. Wu, P. Song,L. Cao, F. Zhou*, H. Zhang*, Z. Shi*, J. Su*. MMP13-targeted siRNA-loaded micelles for diagnosis and treatment of posttraumatic osteoarthritis. Bioactive Materials, 2024, 37: 378-392.
10. S. Sun#, H. Liu#, Y. Hu#, Y. Wang#, M. Zhao, Y. Yuan, Y. Han, Y. Jing, J. Cui*, X. Ren*, X. Chen*, J. Su*. Selection and identification of a novel ssDNA aptamer targeting human skeletal muscle. Bioactive Materials, 2022, 20, 166-178.
