研究方向：
1、聚焦骨关节疾病，开发功能性生物材料和生物墨水
2、构建软骨类器官，高效修复软骨损伤
3、构建病理型类器官，解析骨关节疾病发病机制，实现药物高效筛选
代表性学术成果：
1. Congyi Shen, Jian Wang, Guangfeng Li, Shuyue Hao, Yan Wu, Peiran Song, Yafei Han, Mengmeng Li, Guangchao Wang, Ke Xu, Hao Zhang, Xiaoxiang Ren, Yingying Jing*, Ru Yang*, Zhen Geng*, Jiacan Su*. Boosting cartilage repair with silk fibroin-DNA hydrogel-based cartilage organoid precursor. Bioactive Materials, 2024, 35, 429-444. (ESI高被引论文，热点论文)
2. Congyi Shen, Ziyang Zhou, Ruiyang Li, Shike Yang, Dongyang Zhou*, Fengjin Zhou*, Zhen Geng*, Jiacan Su*. Silk Fibroin-Based Hydrogels for Cartilage Organoids in Osteoarthritis Treatment. Theranostics, 2025, 15(2): 560-584. (ESI高被引论文，热点论文)
3. Ziyang Zhou, Peiran Song, Yan Wu, Miaomiao Wang, Congyi Shen, Zhixin Ma, Xiaoxiang Ren, Xiuhui Wang, Xiao chen, Yan Hu, Zuhao Li, Qin Zhang*, Mengmeng Li*, Zhen Geng*, Jiacan Su*. Dual-network DNA-Silk fibroin hydrogels with controllable surface rigidity for regulating chondrogenic differentiation. Materials Horizons, 2024, 11, 1465-1483. (ESI高被引论文)
4. Congyi Shen, Qirong Zhou, Xiang Wu, Xinyu Han, Qin Zhang, Xiao Chen, YuXiao Lai, Long Bai, Yingying Jing, Jianhua Wang*, Chenglong Wang*, Zhen Geng*, Jiacan Su*. Accelerating Cartilage Regeneration with DNA-SF Hydrogel Sustained Release System-Based Cartilage Organoids. Military Medical Research, 2025, 12, 39.
5. Yili Wang, Qiushui Lin, Hao Zhang, Sicheng Wang, Jin Cui, Yan Hu, Jinlong Liu, Mengmeng Li, Kun Zhang, Fengjin Zhou*, Yingying Jing*, Zhen Geng*, Jiacan Su*. M2 macrophage-derived exosomes promote diabetic fracture healing by acting as an immunomodulatory. Bioactive Materials, 2023, 28, 273-283. (ESI高被引论文，热点论文)
6. Xu Xue, Hao Zhang, Han Liu, Sicheng Wang, Jiadong Li, Qirong Zhou, Xiao Chen, Xiaoxiang Ren, Yingying Jing, Yonghui Deng*, Zhen Geng*, Xiuhui Wang*, Jiacan Su*. Rational Design of Multifunctional CuS Nanoparticle-PEG Composite Soft Hydrogel-Coated 3D Hard Polycaprolactone Scaffolds for Efficient Bone Regeneration. Advanced Functional Materials, 2022, 2202470. (ESI高被引论文)
7. Zhen Geng, Luli Ji, Zhaoyang Li*, Jing Wang*, Hongyan He, Zhenduo Cui, Xianjin Yang, Changsheng Liu. Nano-needle strontium-substituted apatite coating enhances osteoporotic osseointegration through promoting osteogenesis and inhibiting osteoclastogenesis. Bioactive Materials, 2021, 6, 905-915.
8. Yili Wang, Hao Zhang, Yan Hu, Yingying Jing*, Zhen Geng*, Jiacan Su*. Bone repair biomaterials: a perspective from immunomodulatory. Advanced Functional Materials, 2022, 32, 2208639.
9. Kai Dai, Zhen Geng, Wenchao Zhang, Xue Wei, Jing Wang*, Guangjun Nie*, Changsheng Liu*. Biomaterial design for regenerating aged bone: materiobiological advances and paradigmatic shifts. National Science Review, 2024, 11, nwae076.
10. Mengmeng Li, Hongshi Ma, Fei Han, Dong Zhai, Bingjun Zhang, Yuhua Sun, Tian Li, Lei Chen, Chengtie Wu*. Microbially catalyzed biomaterials for bone regeneration. Advanced Materials, 2021, 33: 2104829.
